Bliss - 5 Pack Supports Biochemical Reactions Requiring Methyl Groups* Supports Neurotransmitter Synthesis and Healthy Mood* Facilitates Conversion of Homocysteine to Glutathione* Supports Liver Health and Function* Promotes Joint Comfort* Bliss is... Read more
Biochemical Reactions Requiring Methyl Groups
Neurotransmitter Synthesis and Healthy Mood
Conversion of Homocysteine to Glutathione
Liver Health and Function
*MAY ALSO BE MIXED WITH SMALL AMOUNT OF WATER
SAMe is the “universal” methyl donor for biochemical reactions throughout the body. This methyl transfer, or “transmethylation,” is critical to reactions involving proteins, phospholipids, DNA, RNA, creatine, hormones, development of cell membranes, degradation of histamine, and formation of norepinephrine and dopamine. Eighty-five percent of transmethylation takes place in the liver, and healthy SAMe levels appear to be essential to liver health and function.
Bliss' SAM-e contains a minimum of 70% of the SS isomer of SAMe, the form the body can use most readily. This relatively high concentration from Gnosis’ Adomix® not only makes SAM-e particularly bioavailable but also cost-effective. Each capsule is sealed in a nitrogen-purged blister pack to maximize protection from the environment.
SAMe is considered to be “critical” for synthesis of glutathione, a principal component of antioxidant and detoxification systems in the body. Following donation of a methyl group, SAMe is converted to S-adenosylhomocysteine (SAH). This biochemical reaction promotes the transsulfuration pathway in the liver that generates glutathione. Further metabolism of SAH involves trimethylglycine (TMG), also known as betaine anhydrous. TMG plays an important role in maintaining a healthy SAMe:SAH ratio in the liver.
Trimethylglycine is a naturally occurring compound (glycine attached to three methyl groups) that is found in naturally and can be produced in the body from the precursor choline. TMG is thought to protect liver cells, support homocysteine metabolism and cardiovascular health, and may also support a healthy mood due to its role in SAMe metabolism. When TMG donates a single methyl group, it is converted to dimethylglycine (DMG), which is capable of donating two methyl groups. TMG is thought to stimulate activity of the enzyme betaine-homocysteine methyltransferase (BHMT). BHMT, found in abundance in a healthy liver, is used by TMG to donate a methyl group to homocysteine. Once TMG adds a methyl group to homocysteine to produce methionine, the methionine can then be converted to SAMe. A randomized, double-blind, crossover study of healthy volunteers suggested that TMG supplementation (at doses of 3 g and 6 g/d) has a dose-dependent effect on serum TMG levels and a significantly positive effect on maintaining healthy homocysteine levels. Together, SAMe and TMG provide an abundant source of methyl groups and ultimately support a wide variety of biochemical reactions in the body.
Bliss - 5 Pack
Bliss is a sweet, yet slightly tart lemon-flavored powder. This shot contains naturally occurring substances that act as methyl donors during vital biochemical processes in the body. Methylation is essential for normal cell health and function but can decline with age or chronic alcohol consumption or can be limited in some individuals due to their genetic makeup.
Bliss delivers methyl groups, which are needed for the synthesis of neurotransmitters, proteins, nucleic acids, and phospholipids. It supports glutathione production, liver health, joint comfort, and a healthy mood. TMG ultimately supports cardiovascular and neurological health, as well as normal cell-life regulation.
Xylitol, citric acid, malic acid, stearic acid, silica, natural lemon flavor, and turmeric extract (for color).
Does NOT Contain:
Wheat, gluten, yeast, soy protein, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Dissolve the contents of one stick pack in 6-12 oz of water according to preferred sweetness. Consume the effervescent drink once daily, or use it as directed by your healthcare practitioner.
Keep closed in a cool, dry place out of reach of children.
Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Caffeine should not be combined with synephrine or ephedrine. Use cautiously if you have a history of abnormal heart rhythm. Do not use it if the tamper seal is damaged.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.nt.*
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease.